
Nikki Holtke, FNP
Family Medicine
About Nikki Holtke
About The Provider
Nikki Holtke, CNP received her Masters of Science from Wright State University, Family Nurse Practitioner, in 2006. Nikki received her Bachelors of Science in nursing from Miami University in 1996. She is certified as a Family Nurse Practitioner by the American Nurses Credentialing Center. She has been a registered nurse since 1992. She brought 14 years experience as a critical care nurse to her career as a Family Nurse Practitioner.
Networks
Member of Premier Physician Network

Practice Website
Locations
- Centerville Family Medicine
- 2350 Miami Valley Dr, Suite 530, Centerville, OH 45459
- phone: 937-435-3546
Highlights
Age Groups Seen
- Infant 0-2
- Child 2-12
- Adolescent 12-18
- Adult 18-65
- Older Adult >65
Languages
- English
Gender
FemaleInsurance
- Aetna
- Amerihealth Medicaid
- Anthem
- Buckeye Health Plan - Medicaid and Medicare only
- Caresource
- Champ VA
- Cigna
- CommuniCare I-SNP
- Devoted Health
- First Health/Coventry
- Healthsmart
- Healthspring
- Humana - Medicaid and Medicare only
- Medicaid Ohio Traditional
- Medical Mutual
- Medicare A and B
- MediGold
- Ohio Health Choice/Ohio PPO Connect
- Paramount - Medicare Only
- Perennial Advantage I-SNP - Medicare Only
- Private Healthcare Systems
- Tricare/Humana Military
- UMR
- United Behavioral/Optum Health
- United HealthCare
- WellCare Medicare
Ratings & Reviews
4.9 out of 5
165 ratings, 46 reviewsThe Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.
- 5 out of 5 starsReviewed on 3/15/2026
Leslie Holtke is the BEST. She genuinely cares about her patients and it shows with the amount of time she spends with them.
- 5 out of 5 starsReviewed on 3/14/2026
Leslie Holtke always spends a considerable amount of time on my appointments, I appreciate her dedication to giving me the best healthcare!
- 5 out of 5 starsReviewed on 3/6/2026
Great experience
- 5 out of 5 starsReviewed on 2/21/2026
Staff and Leslie are great . Very friendly and helpful
- 5 out of 5 starsReviewed on 2/7/2026
Ms. Holtke is a great primary care provider. She takes the time to listen, took the time to look up information to address a health concern I had, reviewed all of my lab results, and reviewed my meds. I appreciate her caring and her willingness to treat me like a partner in my healthcare. She's the best!
- 5 out of 5 starsReviewed on 1/14/2026
Always fast friendly and efficient!
- 5 out of 5 starsReviewed on 1/10/2026
Professional but above all caring. Listened and answered.
- 5 out of 5 starsReviewed on 12/18/2025
When my appointment was finished I was told to have a happy holiday it is near Christmas , I would rather have people say Merry Christmas . I'm tired of catering to the small percentage that would be offended.
- 5 out of 5 starsReviewed on 12/14/2025
The staff here has always treated me with kindness and respect.
- 5 out of 5 starsReviewed on 12/7/2025
Nikki is the best cnp,i have ever had.since i had just come from pre testing for a operation next week there was no need for her to send me for any other blood,or other tests
- 5 out of 5 starsReviewed on 12/11/2025
Always a pleasure walking into the office. From beginning to end. Much appreciated.
- 5 out of 5 starsReviewed on 12/3/2025
FINE !
- 5 out of 5 starsReviewed on 12/3/2025
Excellent.
- 5 out of 5 starsReviewed on 11/30/2025
Staff were wonderful in helping me to schedule a virtual appt. They were caring and compassionate.
- 5 out of 5 starsReviewed on 11/24/2025
Dr. Nicolle is very personable and real and I appreciate all her input and discussions
- 5 out of 5 starsReviewed on 11/15/2025
The best
- 5 out of 5 starsReviewed on 11/6/2025
Very professional, informative, and very friendly staff
- 5 out of 5 starsReviewed on 10/31/2025
Great experience! Nikki and all the staff are wonderful!
- 5 out of 5 starsReviewed on 10/21/2025
Very knowledgeable, friendly, personable provider.
- 5 out of 5 starsReviewed on 10/19/2025
I felt very welcome
- 5 out of 5 starsReviewed on 10/15/2025
Everyone in this office knows their job and does in very professionally.
- 5 out of 5 starsReviewed on 10/12/2025
None better!
- 5 out of 5 starsReviewed on 10/9/2025
Great staff and caring about my health! They take the time to listen and answer your questions
- 5 out of 5 starsReviewed on 9/27/2025
The staff at Centerville Family Medicine is exceptional. Friendly, helpful, efficient and responsive.
- 5 out of 5 starsReviewed on 9/26/2025
My visits are always professional and efficient. I appreciate the caring approach of my provider and the office staff. Upon the conclusion of my visit, I was able to leave in comfort-having all of my questions answered and a clear plan of care to follow. Follow up needs were well established prior to my departure.
- 5 out of 5 starsReviewed on 9/21/2025
Great office
- 5 out of 5 starsReviewed on 9/8/2025
All great.
- 5 out of 5 starsReviewed on 8/9/2025
Great experience.
- 5 out of 5 starsReviewed on 8/8/2025
I needed to see a doctor that day and Dr. Holtke set up an appointment that exact day for me. Dr. Holtke was very nice and listened to me.
- 5 out of 5 starsReviewed on 7/26/2025
I have been going to this provider for a few years and have always been highly satisfied with the care I receive. The staff is always nice and efficient. My care provider listens to me, explains things in detail and is very proactive.
- 5 out of 5 starsReviewed on 7/29/2025
All staff members were courteous and professional.
- 5 out of 5 starsReviewed on 7/19/2025
Nikki is always really helpful and listens to concerns. She takes patients' health seriously and puts them in touch with specialists if needed.
- 5 out of 5 starsReviewed on 7/17/2025
She is great!!! Explains everything and makes sure you understand. I feel very comfortable around her. She answers all my questions and offers good advice. I am very happy to have her as my doctor.
- 5 out of 5 starsReviewed on 7/12/2025
Everyone was so friendly and professional.
- 4 out of 5 starsReviewed on 7/9/2025
Stop pushing masks. I'm having trouble breathing and all the woman behind the desk was concerned about is that I had a mask. How sad it is that these dipsticks think that protects anyone. Removing it to blow my nose and cough just sent more germs into the air and yes I was really sick with lots of germs to share Listening to the troubles of the personal lives the desk bimbets absolutely does not lend itself to healing and I waited over an hour in the waiting area. An hour, couldn't breathe. I will not wear a mask again.
- 5 out of 5 starsReviewed on 7/2/2025
I feel very welcome.
- 5 out of 5 starsReviewed on 7/11/2025
My medical provider is kind, caring, and listens intently to me. She instills confidence in me in her abilities to assist me in my medical needs.
- 3 out of 5 starsReviewed on 7/2/2025
The attending nurse was awesome and professional.
- 5 out of 5 starsReviewed on 6/26/2025
Everything was fine - enough time taken, referral to another Dr. for my issue after checking out my problem
- 5 out of 5 starsReviewed on 6/15/2025
I have all my confidence in my provider Holtke NP she is awesome very knowledgeable and friendly.
- 5 out of 5 starsReviewed on 6/9/2025
Great people! Always professional and polite. Always concerned with my needs.
- 5 out of 5 starsReviewed on 6/9/2025
Health care at it finest
- 5 out of 5 starsReviewed on 6/9/2025
very welcoming
- 5 out of 5 starsReviewed on 5/9/2025
Nicolle is a great nurse practitioner she is certainly a asset to your facility, i couldn't ask for better health practitioner.
- 5 out of 5 starsReviewed on 5/8/2025
Love my physician Holtke and the office! Thank you!
- 5 out of 5 starsReviewed on 5/5/2025
Definitely a good experience and always seeking the best path forward health-wise



